Phthalimide acetyl chloride
Phthalimide acetyl chloride
CAS: 6780-38-7
Molecular Formula: C10H6ClNO3
Phthalimide acetyl chloride - Names and Identifiers
Phthalimide acetyl chloride - Physico-chemical Properties
| Molecular Formula | C10H6ClNO3 |
| Molar Mass | 223.61 |
| Density | 1.504±0.06 g/cm3(Predicted) |
| Melting Point | 84-85 °C |
| Boling Point | 190-192 °C(Press: 15 Torr) |
| Flash Point | 161.4°C |
| Solubility | Chloroform, Dichloromethane |
| Vapor Presure | 7.14E-05mmHg at 25°C |
| Appearance | Solid |
| Color | White |
| pKa | -2.56±0.20(Predicted) |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.614 |
| Physical and Chemical Properties | Light yellow to white crystalline powder |
Phthalimide acetyl chloride - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2923 8/PG 3 |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
Phthalimide acetyl chloride - Introduction
Phthalimide acetyl chloride is an organic compound with the chemical formula C10H6ClNO2. The following is a description of the nature, use, preparation and safety information of the substance:
Nature:
Phthalimide acetyl chloride is a colorless to slightly yellow crystal or solid. It can be dissolved in most organic solvents and is stable in water and acidic conditions.
Use:
Phthalimide acetyl chloride has a wide range of applications in the field of organic synthesis. It can be used as an important intermediate, often used in the synthesis of drugs, dyes and pesticides and other organic compounds. This compound can be subjected to an acylation reaction to introduce an acetyl group into an organic molecule, thereby changing the nature and function of the molecule.
Preparation Method:
Typically, Phthalimide acetyl chloride is prepared by reacting phthalimide with acetic acid chloride. The specific step is that phthalimide is reacted with excess acetic acid chloride, and a pure product is obtained by distillation, crystallization and other process steps after the reaction is complete.
Safety Information:
Phthalimide acetyl chloride under normal operating conditions generally do not produce direct harm to the human body. However, it is an organic compound, so pay attention to safe handling measures during use, including wearing appropriate protective equipment and avoiding inhalation, contact with skin and eyes. At the same time, it should be stored in a closed container, away from combustibles and oxidants. If necessary, operate in a well-ventilated environment. It is best to refer to the relevant safety data sheets and chemical labels for more detailed safety information.
Nature:
Phthalimide acetyl chloride is a colorless to slightly yellow crystal or solid. It can be dissolved in most organic solvents and is stable in water and acidic conditions.
Use:
Phthalimide acetyl chloride has a wide range of applications in the field of organic synthesis. It can be used as an important intermediate, often used in the synthesis of drugs, dyes and pesticides and other organic compounds. This compound can be subjected to an acylation reaction to introduce an acetyl group into an organic molecule, thereby changing the nature and function of the molecule.
Preparation Method:
Typically, Phthalimide acetyl chloride is prepared by reacting phthalimide with acetic acid chloride. The specific step is that phthalimide is reacted with excess acetic acid chloride, and a pure product is obtained by distillation, crystallization and other process steps after the reaction is complete.
Safety Information:
Phthalimide acetyl chloride under normal operating conditions generally do not produce direct harm to the human body. However, it is an organic compound, so pay attention to safe handling measures during use, including wearing appropriate protective equipment and avoiding inhalation, contact with skin and eyes. At the same time, it should be stored in a closed container, away from combustibles and oxidants. If necessary, operate in a well-ventilated environment. It is best to refer to the relevant safety data sheets and chemical labels for more detailed safety information.
Last Update：2024-04-09 21:32:43
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